Acelex Powder for Suspension 125 mg/5 ml

Acelex Powder for Suspension is a first-generation cephalosporin antibiotic containing Cephalexin (125 mg/5 ml) manufactured by ACME Laboratories Ltd. This powder for suspension formulation treats bacterial infections in respiratory, urinary, skin, and ENT systems. Priced at ৳77.50 per unit, it offers cost-effective therapy while requiring proper storage in cool, dry conditions.

This antibiotic disrupts bacterial cell wall synthesis by inhibiting peptidoglycan cross-linking. Effective against staphylococci and streptococci, Acelex is prescribed for bronchitis, UTIs, otitis media, and bone infections. Its twice-daily dosing option enhances patient compliance, especially for adults managing cystitis or pharyngitis.

Dosage guidelines vary by age and severity. Adults typically take 250–500 mg every 6 hours, while pediatric doses (25–100 mg/kg/day) depend on weight. For example, a 20 kg child may receive 125–250 mg four times daily. Severe infections may require up to 6 g/day for adults under medical supervision.

Common side effects include gastrointestinal discomfort, rash, and transient liver enzyme changes. Rare risks involve pseudomembranous colitis and neutropenia. Pregnant/nursing women should use it cautiously, though FDA pregnancy Category B classification suggests relative safety when benefits outweigh risks.

As a Cephalexin brand, Acelex has alternatives like Acelex 250 mg and 500 mg tablets. Patients should complete the full course, especially for streptococcal infections requiring 10-day treatments. Always shake the suspension well and use calibrated measuring devices for accurate dosing.

Adults: 250-500 mg every 6 hours. Children: 25-100 mg/kg/day (max 4 g/day). Renal impairment requires dose adjustment. Administer with food to reduce GI upset. Treat streptococcal infections for at least 10 days.

Side effects include nausea, vomiting, diarrhoea and abdominal discomfort. Symptoms of pseudomembranous colitis may appear either during or after antibiotic treatment. Skin rash, angio oedema, rise in serum aminotransferases, eosinophilia, neutropenia have been reported very rarely. Superinfection with resistant micro organisms, particularly candida may follow the treatment.

Pregnancy Category B. Use cautiously during lactation as excreted in breast milk.

Adjust dose in renal impairment based on creatinine clearance. Monitor hepatic/renal function during prolonged therapy. May cause false-positive urine glucose tests.

Pediatric: Weight-based dosing. Geriatric: Assess renal function. Renal impairment: Dose adjustment required. Hepatic impairment: Standard dose applicable.