Acerux-H Cream 5% + 1%

Acerux-H Cream is a topical medication combining Acyclovir (5%) and Hydrocortisone (1%). Manufactured by Opsonin Pharma Ltd, it treats recurrent herpes labialis (cold sores) by reducing ulcer formation and accelerating healing. Available as a cream, it’s priced at ৳35.00 per unit, offering affordable access to dual-action therapy.

The cream inhibits herpes virus replication via Acyclovir’s antiviral properties while Hydrocortisone alleviates inflammation. Apply it 5 times daily for 5 days, starting at the first sign of tingling or redness. Store below 30°C, away from light and moisture. Clinical studies show efficacy in adults and children aged 6+ years.

Key pharmacological actions include:

• Competitive inhibition of viral DNA polymerase
• Termination of viral DNA chain growth
• Reduced inflammation via glucocorticoid activity

Common side effects (<1%) involve mild skin reactions like dryness, burning, or erythema. Pregnancy Category B status indicates minimal systemic absorption, but consult a doctor during lactation. No major drug interactions reported. For alternatives, explore Acyclovir + Hydrocortisone generics.

Apply 5 times daily (every 4 hours) for 5 days in adults & children ≥6 years. Do not adjust dosage without consultation. Gently rub on affected area.

The following most common adverse reactions (<1%) were local skin reactions like drying or flaking of the skin; burning or tingling, erythema; pigmentation changes, application site reactions including signs and symptoms of inflammation.

Pregnancy Category B. Use cautiously during lactation. excretion in breast milk unknown; consult physician.

Discontinue if no improvement in 2 weeks. Monitor immunocompromised patients. Wash hands after applying cream.

Safety in children <6 years unestablished. No specific guidelines for elderly/hepatic/renal impairment—use with caution.