ACF Tablet 100 mg

ACF Tablet is a widely-used NSAID containing Aceclofenac 100 mg, manufactured by Decent Pharma Laboratories Ltd. It effectively treats osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, and acute pain conditions like dental pain or lower back pain. Priced at ৳4.00 per tablet, this tablet form medication offers affordable inflammation management.

As a cyclooxygenase (COX) enzyme inhibitor, ACF Tablet blocks prostaglandin synthesis, reducing pain and swelling. The film-coated variant requires twice-daily dosing, while extended-release tablets (200 mg) are taken once daily. Always consult a physician for personalized dosage guidance, especially for long-term use or pre-existing conditions.

Key drug interactions include increased plasma levels of lithium, digoxin, and methotrexate. Concurrent use with diuretics or anticoagulants may require monitoring. Notable side effects include mild gastrointestinal discomfort, nausea, and skin rashes. Store tablets in a dry, cool place away from children’s reach to maintain efficacy.

Adults: Extended-release tablet 200 mg once daily. Film-coated tablet 100 mg twice daily. Dose adjustment required in hepatic/renal impairment. Take after meals. Maximum 10 days use without medical supervision.

ACF is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.

Pregnancy Category C – use only if potential benefit justifies risk. Contraindicated during lactation. Consider safer alternatives.

Monitor elderly patients (>60 years) and those with hepatic/renal impairment. Consider misoprostol for gastric protection in high-risk groups.

Pediatric safety unestablished. Start with low dose in geriatrics. 50% dose reduction in renal impairment. Avoid in severe hepatic dysfunction.