Aclene Cream 0.1%

Aclene Cream is a topical medication containing Adapalene 0.1%, manufactured by Drug International Ltd. It is specifically formulated for treating acne on the face, chest, and back. Priced at ৳60.20 per unit, this cream offers an affordable solution for managing mild to moderate acne through targeted action on skin cells.

The cream works by binding to retinoid receptors, normalizing follicular cell differentiation, and preventing microcomedone formation. Clinical studies show it reduces inflammation, keratinization, and comedones – key factors in acne development. Apply a thin layer to affected areas once daily at bedtime for optimal results.

Key features:

• Contains third-generation retinoid Adapalene
• Minimal systemic absorption (0.04 ng/ml)
• Suitable for long-term use
• Available as 15g/30g cream formulations

Common side effects include temporary erythema, peeling, and dryness, which typically subside with continued use. Avoid concurrent use with sulfur-containing products or abrasive cleansers. Store below 25°C in original packaging.

Apply 0.1% cream once daily at night to affected areas in adults and adolescents ≥12 years. 0.3% formulation can be applied to entire face. Continue treatment for up to 3 months until acne clears. No dosage adjustment needed in renal/hepatic impairment.

Erythema, scaling, dryness, pruritus, burning sensation, skin irritation, stinging unburn, acne flares, etc. are commonly seen during the first month of therapy but usually lessen with continued use of the medication.

Use during pregnancy only if clearly needed (Pregnancy Category C). Avoid during lactation – unknown excretion in breast milk.

Use SPF 30+ sunscreen when outdoors. Ensure skin is dry for 15 mins before application. Avoid contact with eyes/nasal mucosa. Manufactured by Drug International Ltd.

Safety not established in children <12 years. Standard dosing applies to elderly. No special precautions needed in renal/hepatic impairment.