Acliz Plus Tablet 25 mg + 50 mg

Acliz Plus is an anti-emetic tablet combining Meclizine (25mg) and Pyridoxine (50mg), manufactured by Aristopharma Ltd. Priced at ৳3.50 per unit, it effectively treats nausea, vomiting, motion sickness, and vertigo linked to vestibular disorders. This tablet works by blocking histamine receptors and reducing inner ear sensitivity.

The drug’s pharmacology includes antihistaminic, anticholinergic, and antiemetic properties. It suppresses the vomiting center in the brain and enhances Vitamin B6 supplementation. Ideal for radiation-induced nausea, it’s taken 2–12 hours before therapy. For motion sickness, a 25–50mg dose 1 hour pre-travel is recommended.

Dosage guidelines for adults and children above 12:

• Nausea/vomiting: 25–50mg daily
• Motion sickness: 25–50mg pre-journey
• Vertigo: 25–100mg in divided doses

Common side effects include drowsiness and dry mouth. Avoid alcohol and CNS depressants. During pregnancy (Category B), it’s preferred for morning sickness but requires caution in lactation. Overdose may cause seizures—seek immediate care.

Store below 30°C, away from moisture. Explore alternatives under Meclizine + Pyridoxine generics. Priced at ৳35 per strip, Acliz Plus offers affordable relief for vestibular and chemotherapy-related nausea.

Adults & 12+ years: 25-50 mg daily for nausea. 25-50 mg 1 hour before travel. 50 mg 2-12 hours before radiation therapy. 25-100 mg in divided doses for vertigo. Not recommended below 12 years.

Drowsiness, dry mouth and, on rare occasions, blurred vision have been reported.

Pregnancy Category B. Insufficient data for lactation.

Avoid driving/machinery operation. Monitor blood pressure with Aristopharma guidelines. Abstain from alcohol.

Reduce dose in elderly. Adjust dose in hepatic/renal impairment. Pediatric safety unestablished.

Symptoms: Extreme excitability, seizures, drowsiness and hallucinations.
Treatment: Appropriate supportive and symptomatic treatment. Consider dialysis