Aclobet Ointment 0.05%

Aclobet is a topical corticosteroid ointment containing Clobetasol Propionate 0.05%, manufactured by ACME Laboratories Ltd. Priced at ৳150.00 per 25g tube, it treats inflammatory skin conditions like psoriasis and lichen planus. This high-potency steroid reduces itching, swelling, and redness by suppressing inflammatory responses.

Key indications include localized plaque psoriasis, lichen planus, and recalcitrant dermatoses. Apply a thin layer twice daily to affected areas. Limit use to 2 weeks to avoid skin thinning. Weekly dosage should not exceed 50g. For scalp solutions, massage gently and wash after 15 minutes.

Potential side effects include skin atrophy, burning, and hyperpigmentation. Avoid occlusive dressings unless prescribed. Pregnant women should use it only if benefits outweigh fetal risks. Store below 30°C, away from moisture. Consult doctors if symptoms persist beyond 7 days.

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Apply thin layer twice daily to affected areas. Maximum 2 weeks continuous use. For scalp: Spray/ointment up to 50ml/week. Pediatric use beyond 5 days requires medical reassessment. Avoid occlusive dressings except for resistant cases.

• As with other topical corticosteroids prolonged use of large amounts, or treatment of extensive areas can result in sufficient systemic absorption to produce the features of hypercorticism.
• Prolonged and intensive treatment with a highly active corticosteroid preparation may cause local atrophic changes in the skin such as thinning, striae and dilatation of the superficial blood vessels, particularly when occlusive dressings are used or when skin folds are involved.
• In rare instances, treatment of psoriasis with corticosteroids (or its withdrawal) is thought to have provoked the pustular form of the disease.
• There are reports of pigmentation changes and hypertrichosis with topical steroids. Aclobet is usually well tolerated, but if signs of hypersensitivity appear, application should be stopped immediately. Exacerbation of symptoms may occur.

Pregnancy Category C: Use only if potential benefit justifies risk. Excretion in breast milk unknown – caution during lactation.

Avoid periocular application. Monitor psoriasis patients for flare-ups. Concurrent antimicrobial therapy needed for infected lesions. Regular adrenal function tests advised in prolonged use.

Pediatric use restricted to >1 year olds. Geriatric patients need skin integrity monitoring. Dose adjustment unnecessary in hepatic/renal impairment.

Acute overdosage is very unlikely to occur, however, in the case of chronic over-dosage or misuse the features of hypercortisolism may occur and in this situation topical steroid should be discontinued.