Actilac Oral Solution 3.35 gm/5 ml

Actilac Oral Solution is a synthetic disaccharide medication containing Lactulose (3.35g/5ml) manufactured by Healthcare Pharmaceuticals Ltd. This oral solution primarily treats chronic constipation and hepatic encephalopathy by modifying gut flora and reducing ammonia levels. Priced at ৳140.00 per unit, it offers osmotic laxative action with minimal systemic absorption.

The medication works by fermenting in the colon to produce organic acids, softening stools through osmotic water retention. Clinical indications include antibiotic-induced dysbiosis, diverticulosis, and portal-systemic encephalopathy. Dosage varies from 1-30 teaspoons daily based on age and condition severity, requiring medical supervision for long-term use.

Common side effects include initial bloating and abdominal cramps, while overdosing causes diarrhea. As a Category B drug, it’s relatively safe during pregnancy but requires physician approval. Patients should store it away from moisture and sunlight, keeping it inaccessible to children.

Unlike conventional laxatives, Actilac Oral Solution’s unique mechanism minimizes electrolyte imbalance risks when used appropriately. For alternatives to this Lactulose brand, consult healthcare providers about suitable substitutes. Always follow dosage instructions to prevent complications like hypokalemia with cardiac glycosides.

Adults: 3-6 tsp initially for constipation, Children: 1-2 tsp daily. Hepatic cases may require 18-30 tsp/day. Administer on empty stomach. Treatment duration varies based on condition.

Occasionally flatulence, cramp and abdominal discomfort can occur at the beginning of treatment; this is rapidly eliminated by reducing the dose. Overdose can result in diarrhoea. In abuse, loss of electrolytes (primarily potassium).

Pregnancy Category B. Compatible with lactation. Use under medical supervision.

Monitor blood glucose in diabetics. Hepatic impairment requires electrolyte monitoring at high doses.

Pediatric dose adjustments required. No renal dose modification. Hepatic patients may need higher doses under monitoring.

There have been no reports of accidental overdosage. In the event of acute overdosage it is expected that diarrhoea and abdominal cramps would be the major symptoms.