Activa Tablet 100 mg

Activa Tablet is a trusted medication containing Sildenafil Citrate (100 mg) manufactured by Pacific Pharmaceuticals Ltd. Primarily used for erectile dysfunction treatment, it enhances blood flow to the penis during sexual stimulation. Priced at ৳40.00 per tablet, it offers a cost-effective solution with a pack size of 4 tablets (৳160.00 per strip).

This PDE-5 inhibitor works by relaxing penile muscles, requiring sexual arousal for effectiveness. It also treats pulmonary arterial hypertension. Clinical studies show peak plasma concentration within 30-120 minutes. Patients with hepatic/renal impairments or using CYP3A4 inhibitors (e.g., ketoconazole) require dosage adjustments starting from 25 mg.

Key contraindications include concurrent use with nitrates due to severe hypotension risks. Storage guidelines recommend keeping tablets in dry, cool conditions away from children. The tablet form ensures convenient administration with flexible dosing 30 minutes to 4 hours before sexual activity.

Common side effects include headache, flushing, and dyspepsia. Rare but serious cardiovascular events like myocardial infarction have been reported. Patients with pre-existing heart conditions require medical supervision. Activa 50 mg is another variant for dose-sensitive individuals.

LSI Keywords: Activa Tablet uses, Sildenafil brand in Bangladesh, ED treatment cost, Pacific Pharmaceuticals products. Always consult doctors for personalized dosage and contraindication checks.

Initial dose 50 mg taken 1 hour before sexual activity for ED. Max 100 mg/day. Start with 25 mg in hepatic/renal impairment. Pulmonary hypertension: 20 mg every 8 hours.

Body as a whole: face edema, photosensitivity reaction, shock, asthenia, pain, chills, accidental fall, abdominal pain, allergic reaction, chest pain, accidental injury.

Cardiovascular: angina pectoris, AV block, migraine, syncope, tachycardia, palpitation,hypotension, postural hypotension, myocardial ischemia, cerebral thrombosis, cardiac arrest, heart failure, abnormal electrocardiogram, cardiomyopathy.

Digestive: vomiting, glossitis, colitis, dysphagia, gastritis, gastroenteritis, esophagitis, stomatitis, dry mouth, liver function tests abnormal, rectal hemorrhage, gingivitis.

Hemic and Lymphatic: anemia and leukopenia.

Metabolic and Nutritional: thirst, edema, gout, unstable diabetes, hyperglycemia, peripheral edema, hyperuricemia, hypoglycemic reaction, hypernatremia.

Musculoskeletal: arthritis, arthrosis, myalgia, tendon rupture, tenosynovitis, bone pain,myasthenia, synovitis.

Nervous: ataxia, hypertonia, neuralgia, neuropathy, paresthesia, tremor, vertigo, depression, insomnia, somnolence, abnormal dreams, reflexes decreased, hyperesthesia.

Respiratory: asthma, dyspnea, laryngitis, pharyngitis, sinusitis, bronchitis, sputum increased, cough increased.

Skin and Appendages: urticaria, herpes simplex, pruritus, sweating, skin ulcer, contact dermatitis, exfoliative dermatitis.

Special Senses: sudden decrease or loss of hearing, mydriasis, conjunctivitis, photophobia, tinnitus, eye pain, ear pain, eye hemorrhage, cataract, dry eyes.

Urogenital: cystitis, nocturia, urinary frequency, breast enlargement, urinary incontinence, abnormal ejaculation, genital edema and anorgasmia.

Cardiovascular and cerebrovascular: Serious cardiovascular, cerebrovascular, and vascular events, including myocardial infarction, sudden cardiac death, ventricular arrhythmia, cerebrovascular hemorrhage, transient ischemic attack, hypertension, subarachnoid and intracerebral hemorrhages, and pulmonary hemorrhage have been reported post-marketing in temporal association with the use of Activa. Most, but not all, of these patients had preexisting cardiovascular risk factors. Many of these events were reported to occur during or shortly after sexual activity, and a few were reported to occur shortly after the use of Activa without sexual activity. Others were reported to have occurred hours to days after the use of Activa and sexual activity. It is not possible to determine whether these events are related directly to Activa, to sexual activity, to the patient’s underlying 23 cardiovascular disease, to a combination of these factors, or to other factors.

Nervous: seizure, seizure recurrence, anxiety, and transient global amnesia.

Urogenital: prolonged erection, priapism and hematuria.

Special Senses: diplopia, temporary vision loss/decreased vision, ocular redness or bloodshot appearance, ocular burning, ocular swelling/pressure, increased intraocular pressure, retinal vascular disease or bleeding, vitreous detachment/traction, paramacular edema and epistaxis.

Pregnancy Category B (contraindicated). Not recommended during lactation.

Cardiac patients require monitoring. Hepatic/renal impairment needs dose adjustment. Monitor for priapism requiring emergency care.

Geriatric patients start with 25 mg. Liver cirrhosis patients use 25 mg dose. Dialysis patients require dose adjustment.

In studies with healthy volunteers of single doses up to 800 mg, adverse events were similar to those seen at lower doses but incidence rates and severities were increased. 24 In cases of overdose, standard supportive measures should be adopted as required. Renal dialysis is not expected to accelerate clearance as Activa is highly bound to plasma proteins and it is not eliminated in the urine.