Flexibac Tablet 25 mg

Flexibac Tablet is a centrally acting muscle relaxant containing Baclofen (25 mg) manufactured by Beacon Pharmaceuticals PLC. Priced at ৳20.06 per unit, it effectively treats spasticity from multiple sclerosis, spinal injuries, and rheumatic disorders. The tablet form ensures easy administration with dosage adjustments based on age and condition severity.

This medication works by activating GABA_B receptors in the spinal cord, reducing muscle spasms and pain. Adults start with 5 mg thrice daily, while children under 10 require tailored dosing. Storage demands include keeping below 30°C, away from moisture and light. LSI keywords like Flexibac Tablet uses and Baclofen brand reflect its therapeutic role.

Key indications include:

• Muscular rigidity in neurodegenerative diseases
• Spasms from cerebrovascular accidents
• Post-injury flexor spasms

Potential side effects range from drowsiness to gastrointestinal discomfort. Drug interactions with CNS depressants or antihypertensives necessitate medical supervision. Pregnant women should use it cautiously, though minimal traces enter breast milk. For overdose, gastric lavage is recommended.

Dosage: Adults start 5 mg TDS, gradually increase to max 100 mg/day. Children (>10y): Similar protocol. Children (<10y): 2.5-60 mg/day based on age. Administer with food.

The most common adverse reactions associated with Flexibac are transient drowsiness, daytime sedation, dizziness, weakness and fatigue.

• Central Nervous System: Headache (<10%), insomnia (<10%), and rarely, euphoria, excitement, depression, confusion, hallucinations, paraesthesia, nightmares, muscle pain, tinnitus, slurred speech, co-ordination disorder, tremor, rigidity, dystonia, ataxia, blurred vision, nystagmus, strabismus, miosis, mydriasis, diplopia, dysarthria, epileptic seizures, respiratory depression.
• Cardiovascular: Hypotension (<10%), rare instances of dyspnoea, palpitation, chest pain, syncope.
• Gastrointestinal: Nausea (approximately 10%), constipation (<10%) and rarely, dry mouth, anorexia, taste disorder, abdominal pain, vomiting, diarrhoea and positive test for occult blood in stool.
• Genitourinary: Urinary frequency (<10%) and rarely, enuresis, urinary retention, dysuria, impotence, inability to ejaculate, nocturia, haematuria.
• Other: Instances of rash, pruritus, ankle oedema, excessive perspiration, weight gain, nasal congestion, visual disturbances, hepatic function disorders and paradoxical increase in spasticity. Muscular hypotonia of a degree sufficient to make walking or movement difficult may occur but is usually relieved by readjusting the dosage. For this purpose, the daytime dosage may be reduced and the evening dosage increased.

Pregnancy Category B3: Use only if benefits outweigh risks. Excreted minimally in breast milk – usually safe during lactation.

Renal patients: Max 5 mg/day. Continue anticonvulsants in epilepsy. Monitor hepatic function. Swallow tablet whole.

Geriatric: Slow dose titration. Renal/Hepatic impairment: Dose reduction required. Pediatric: Age-adjusted dosing.

Gastric lavage is important in case of severe overdose.