Motigen Tablet 10 mg

Motigen Tablet is a gastrointestinal medication containing Domperidone Maleate 10 mg. Manufactured by Novo Healthcare and Pharma Ltd, it effectively treats digestive disorders like delayed gastric emptying, acid reflux, and nausea. Priced at ৳2.01 per tablet (100’s pack: ৳200.61), this tablet formulation offers cost-effective relief for adults and children.

The drug works as a dopamine antagonist, enhancing stomach motility without crossing the blood-brain barrier significantly. This minimizes neurological side effects while alleviating symptoms like bloating, heartburn, and vomiting. It’s particularly useful for Parkinson’s patients experiencing medication-induced nausea.

Dosage: Adults typically take 1-2 tablets (10-20 mg) 15-30 minutes before meals. For acute vomiting, 20 mg every 6-8 hours is recommended. Pediatric doses are weight-adjusted. Maximum treatment duration is 12 weeks. Avoid combining with anticholinergics or opioids to prevent reduced efficacy.

Side Effects: Rare cases include dry mouth (1.9%), headaches (1.2%), or mild skin reactions (0.1%). Elevated prolactin levels may cause breast tenderness. Pregnant women should avoid Motigen due to unconfirmed safety data, though breastfeeding mothers can use it cautiously.

Store below 30°C in moisture-proof packaging. Explore alternatives like Domperidone Maleate brands or consult doctors for persistent symptoms. Known LSI keywords: Motigen Tablet 10 mg, Domperidone Maleate brand, পার্শ্বপ্রতিক্রিয়া.

Adults: 10-20 mg every 6-8 hours (15-30 mins before meals). Pediatric dose: 0.2-0.4 mg/kg body weight. Hepatic impairment requires dose reduction. Maximum treatment duration: 12 weeks.

Side-effects are rare; exceptionally some transient intestinal cramps have been reported. Extrapyramidal phenomena are rare in young children and exceptional in adults: they reverse spontaneously and completely as soon as the treatment is stopped. As the pituitary gland is located outside the blood-brain barrier, domperidone may induce an increase in the plasma prolactin level. In rare case this hyperprolactinaemia may give rise to neuroendocrinological phenomena such as galactorrhoea and gynaecomastia. When the blood-brain barrier is immature (as in infants) or impaired, the possible occurrence of neurological side-effects cannot be totally excluded. Rare allergic reactions, such as rash and urticaria, have also been reported.

Pregnancy Category: Not approved. Lactation: Compatible – minimal secretion in breast milk.

Use cautiously in pediatric/geriatric patients. Dose adjustment needed for hepatic impairment. Monitor prolactin levels during prolonged therapy.

Pediatrics: Avoid in infants <1 year. Hepatic disease: Reduce dose by 50%. Renal failure: Decrease dosing frequency.

Symptoms of overdosage may include drowsiness, disorientation and extrapyramidal reactions, especially in children. In case of overdosage, the administration of activated charcoal, and close observation of the patients are recommended. Anticholinergic, antiparkinson drugs or antihistamines with anticholinergic properties may be helpful in controlling the extrapyramidal reactions.