Motilex Oral Suspension 5 mg/5 ml

Motilex Oral Suspension is a gastrointestinal medication containing Domperidone Maleate (5 mg/5 ml) manufactured by Techno Drugs Ltd. Priced at ৳40.00 per unit, it treats digestive disorders like dyspepsia, nausea, vomiting, and GERD by enhancing gastric motility. This oral suspension accelerates stomach emptying and regulates esophageal sphincter pressure for symptom relief.

Key indications include upper abdominal bloating, acid reflux, and migraine-induced vomiting. Adults take 10–20 mg (10–20 ml) every 6–8 hours before meals. Pediatric doses are weight-adjusted (0.2–0.8 mg/kg). Store below 30°C, away from moisture. Avoid combining with opioid analgesics or anticholinergics due to reduced efficacy.

Common side effects (<1–2% incidence) include dry mouth, headache, and mild diarrhea. Rarely, elevated prolactin levels may cause breast tenderness. Motilex is contraindicated in pregnancy but safe during lactation. For alternatives, explore Domperidone Maleate brands like Motilex 10 mg.

Adults: 10-20 mg 3-4 times daily before meals. Pediatric dose: 0.2-0.8 mg/kg based on weight. Dose adjustment needed in hepatic/renal impairment. Max treatment duration: 12 weeks.

Side-effects are rare; exceptionally some transient intestinal cramps have been reported. Extrapyramidal phenomena are rare in young children and exceptional in adults: they reverse spontaneously and completely as soon as the treatment is stopped. As the pituitary gland is located outside the blood-brain barrier, domperidone may induce an increase in the plasma prolactin level. In rare case this hyperprolactinaemia may give rise to neuroendocrinological phenomena such as galactorrhoea and gynaecomastia. When the blood-brain barrier is immature (as in infants) or impaired, the possible occurrence of neurological side-effects cannot be totally excluded. Rare allergic reactions, such as rash and urticaria, have also been reported.

Pregnancy safety unconfirmed. Safe during lactation but consult doctor. May increase milk production via prolactin.

Monitor infants <1 year for neurological symptoms. Hepatic patients require blood monitoring. ECG advised during prolonged use.

Children: Max 0.4 mg/kg dose. Elderly: Check liver/kidney function. Hepatic impairment: 1-2 doses/day. Renal failure: Increase dosing interval.

Symptoms of overdosage may include drowsiness, disorientation and extrapyramidal reactions, especially in children. In case of overdosage, the administration of activated charcoal, and close observation of the patients are recommended. Anticholinergic, antiparkinson drugs or antihistamines with anticholinergic properties may be helpful in controlling the extrapyramidal reactions.