Moxaclav Powder for Suspension 125 mg + 31.25 mg/5 ml

Moxaclav is a potent antibiotic combination containing Amoxicillin and Clavulanic Acid, manufactured by Square Pharmaceuticals PLC. This powder for suspension formulation (125 mg + 31.25 mg)/5 ml targets bacterial infections in respiratory, urinary, skin, and bone tissues. Priced at ৳220.00 per unit, it offers a cost-effective solution for short-term bacterial management.

The drug combats infections by inhibiting bacterial cell wall synthesis (Amoxicillin) and preventing enzyme degradation (Clavulanic Acid). Ideal for sinusitis, pneumonia, and UTIs, it’s crucial to follow dosage guidelines based on age and infection severity. Store below 25°C, and refrigerate after reconstitution—use within 7 days for optimal efficacy.

Dosage varies: Adults take tablets (625 mg–1 g), while children use suspensions adjusted by weight. Severe infections may require higher doses. Avoid prolonged use beyond 14 days. Common side effects include nausea and diarrhea. Consult a doctor before use during pregnancy or breastfeeding.

Moxaclav interacts with anticoagulants and may reduce oral contraceptive efficacy. For alternatives, explore Amoxicillin + Clavulanic Acid generics. Always complete the prescribed course to prevent antibiotic resistance and ensure thorough infection clearance.

Adults: 625mg tablet every 12 hours. Children (1-6 years): 5ml suspension every 8 hours. Neonates: 30mg/kg/day. Reduce dose by 50% if creatinine clearance 10-30 mL/min. Take with food to reduce GI irritation. Treatment duration typically 5-14 days.

Side effects, as with Amoxicillin, are uncommon and mainly of a mild and transitory nature. Diarrhoea, pseudomembranous colitis, indigestion, nausea, vomiting and candidiasis have been reported, if gastrointestinal side effects occur with oral therapy, that may be reduced by taking Co-amoxiclav at the start of meals. Hepatitis and cholestatic jaundice have been reported rarely but are usually reversible. Urticarial and erythematous rashes sometimes occur. Rarely erythema multiforme, Stevens-Johnson Syndrome and exfoliative dermatitis have been reported. In common with other beta-lactam antibiotics, angioedema and anaphylaxis have been reported.

Pregnancy Category B. Use only if clearly needed. Lactation: Low milk excretion; monitor infant for diarrhea.

Monitor liver enzymes during prolonged therapy. Maintain adequate hydration. Discontinue if persistent diarrhea occurs.

Geriatric patients need renal dose adjustment. Pediatric dosing by weight. Double dosing interval in severe renal impairment. Use cautiously in hepatic dysfunction.

Problems of overdose with Co-amoxiclav are unlikely to occur, if encountered gastrointestinal symptoms and disturbance of the fluid and electrolyte balances may be evident. Co-amoxiclav may be removed from the circulation by haemodialysis.