Moxaclav Tablet 250 mg+125 mg

Moxaclav is a potent antibiotic combination containing Amoxicillin + Clavulanic Acid, manufactured by Square Pharmaceuticals PLC. This tablet formulation (250 mg+125 mg strength) effectively treats bacterial infections in respiratory, urinary, and soft tissue systems.

Priced at ৳25.00 per unit, Moxaclav offers cost-effective therapy. Each strip costs ৳150.00, while bulk packs (4×6) are priced at ৳600.00. The drug requires storage below 25°C, protected from light and moisture, with strict refrigeration guidelines for reconstituted suspensions.

Medical indications span upper/lower respiratory infections, UTIs, skin/soft tissue infections, and post-surgical sepsis. Its dual-action formula combats beta-lactamase producing bacteria through clavulanic acid’s enzyme inhibition, enhancing amoxicillin’s broad-spectrum efficacy against Gram-positive and Gram-negative pathogens.

Dosage varies by age and severity: Adults take 625 mg tablets every 12 hours, while pediatric doses use weight-based suspensions. Notable precautions include potential interactions with oral contraceptives and allopurinol. Common side effects like diarrhea and nausea are generally mild.

As a therapeutic alternative to brands like Moxaclav Forte, this medication demonstrates Square Pharmaceuticals’ commitment to quality pharmaceutical solutions. Always complete prescribed courses to prevent antibiotic resistance.

Adults: 625 mg tablet every 12 hours. Children: 20-45 mg/kg/day (amoxicillin component) divided into 8-12 hourly doses. Renal impairment requires dose adjustment. Tablets can be taken with/without food. Treatment duration varies from 5-14 days based on infection severity.

Side effects, as with Amoxicillin, are uncommon and mainly of a mild and transitory nature. Diarrhoea, pseudomembranous colitis, indigestion, nausea, vomiting and candidiasis have been reported, if gastrointestinal side effects occur with oral therapy, that may be reduced by taking Co-amoxiclav at the start of meals. Hepatitis and cholestatic jaundice have been reported rarely but are usually reversible. Urticarial and erythematous rashes sometimes occur. Rarely erythema multiforme, Stevens-Johnson Syndrome and exfoliative dermatitis have been reported. In common with other beta-lactam antibiotics, angioedema and anaphylaxis have been reported.

Pregnancy Category B. Use only if clearly needed. Compatible with breastfeeding but may cause infant gastrointestinal disturbances.

Monitor liver enzymes during prolonged therapy. Maintain adequate hydration to prevent crystalluria. High rash incidence in patients with EBV infection.

Renal dose adjustment required (reduce dose if GFR <30 mL/min). Use caution in hepatic impairment. Monitor renal function in elderly patients.

Problems of overdose with Co-amoxiclav are unlikely to occur, if encountered gastrointestinal symptoms and disturbance of the fluid and electrolyte balances may be evident. Co-amoxiclav may be removed from the circulation by haemodialysis.