Moxapen Capsule 250 mg

Moxapen Capsule is a widely-used antibiotic containing Amoxicillin Trihydrate 250 mg, manufactured by Nipa Pharmaceuticals Ltd. This capsule formulation effectively treats bacterial infections in ears, throat, skin, and urinary tract. Priced at ৳3.50 per unit (100’s pack: ৳350), it offers affordable therapy while requiring careful storage away from light and moisture.

Clinically, Moxapen inhibits bacterial cell wall synthesis, targeting gram-positive and gram-negative organisms. Its rapid absorption ensures peak plasma concentration within 1-2 hours. Doctors prescribe it for pneumonia, dental abscesses, and H. pylori eradication therapy when combined with clarithromycin and lansoprazole.

Dosage varies by age and condition: Adults take 250 mg thrice daily, while children receive adjusted doses. Severe infections may require 500 mg doses. Notable interactions include reduced contraceptive efficacy and increased amoxicillin levels when combined with probenecid. Mild diarrhea and rashes are common side effects.

As a pregnancy category B drug, Moxapen requires medical supervision for expecting/nursing mothers. The ৳3.50 per capsule cost makes it accessible, though patients must complete prescribed courses to prevent antibiotic resistance. Always consult healthcare providers before using this broad-spectrum penicillin.

Adults: 250-500 mg every 8 hours. Children (<10 years): 20-40 mg/kg/day in 3 divided doses. Pneumonia: 500 mg 8-hourly. Renal dose adjustment required. May take with/without food. Treatment duration typically 5-14 days.

Side effects are mild and transient in nature. This may include diarrhoea, indigestion or occasionally rash. Pseudo-membranous colitis has been reported rarely.

Pregnancy Category B. Excreted in breast milk – use cautiously during lactation. Consult physician for risk-benefit analysis.

Monitor for superinfections. Reduce dose in renal impairment. Discontinue if antibiotic-associated colitis occurs. Regular blood monitoring recommended.

Pediatrics: Weight-based dosing. Geriatrics: Assess renal function. Renal impairment: Extend dosing interval when GFR <30. Hepatic impairment: No specific adjustment needed.