Moxibac Ophthalmic Solution 0.5%

Moxibac is a widely-used ophthalmic antibacterial solution containing 0.5% Moxifloxacin Hydrochloride. Manufactured by Popular Pharmaceuticals Ltd, it effectively treats bacterial conjunctivitis caused by Gram-positive, Gram-negative, and Chlamydia trachomatis infections. Priced at ৳160.00 per unit, this eye drop offers targeted therapy with a 7-day treatment regimen.

As a ophthalmic solution, Moxibac works by inhibiting bacterial DNA gyrase (Topoisomerase II) and Topoisomerase IV enzymes, preventing DNA replication. Its broad-spectrum efficacy covers pathogens like Staphylococcus aureus, Streptococcus pneumoniae, and Haemophilus influenzae. Users should apply one drop thrice daily in affected eyes.

Common side effects (1-6% patients) include conjunctival inflammation, blurred vision, and eye dryness. Systemic reactions like fever and pharyngitis occur less frequently. The drug requires storage below 25°C without freezing. Patients must avoid dropper tip contamination and discard bottles after one month of opening.

While no significant drug interactions with CYP450 enzymes are reported, caution applies during pregnancy/lactation. For detailed information on Moxifloxacin Hydrochloride, consult healthcare providers. Moxibac remains contraindicated in quinolone-sensitive individuals.

Adults: Drops – 1 drop in affected eye 3 times daily for 7 days. Ointment – Apply 3 times daily for first 2 days, then twice daily for next 5 days. Wash hands before use and avoid touching dropper tip.

The most frequently reported ocular adverse events were conjunctivitis, decreased visual acuity, dry eye, keratitis, ocular discomfort, ocular hyperemia, ocular pain, ocular pruritus, subconjunctival hemorrhage, and tearing. These events occurred in approximately 1-6% of patients. Nonocular adverse events reported at a rate of 1-4% were fever, increased cough, infection, otitis media, pharyngitis, rash, and rhinitis.

Pregnancy safety unestablished. Avoid during lactation due to potential milk secretion. Use under medical supervision.

Discontinue contact lens use during treatment. Clean dropper tip after each use. Store in original packaging from Popular Pharmaceuticals below 25°C. Consult doctor if no improvement within 48 hours.

Limited data for pediatric/geriatric use. No dosage adjustment needed in renal/hepatic impairment, but monitor closely.