NapaDol Tablet 325 mg + 37.5 mg

NapaDol Tablet is a combination analgesic containing Paracetamol + Tramadol Hydrochloride (325 mg + 37.5 mg). Manufactured by Beximco Pharmaceuticals Ltd, this tablet treats moderate to severe acute pain in adults. It is priced at ৳8.00 per unit, with a strip price of ৳96.00 and pack size options for bulk purchases.

The drug combines Paracetamol’s antipyretic and analgesic properties with Tramadol’s opioid-like pain relief. Paracetamol inhibits prostaglandin synthesis via COX enzymes, while Tramadol acts on μ-opioid receptors and inhibits serotonin/norepinephrine reuptake. This dual mechanism ensures rapid and effective pain management for short-term use (≤5 days).

Dosage guidelines recommend 1-2 tablets every 4-6 hours, not exceeding 8 tablets daily. For acute pain, 2 tablets every 4-6 hours may be used temporarily. It can be taken with or without food. Common side effects include dizziness, constipation, and dry mouth. Severe reactions require immediate medical attention.

Store NapaDol in a cool, dry place away from children. Pregnant women (Category C) should use it only if benefits outweigh fetal risks. Breastfeeding mothers are advised to avoid it due to unknown infant safety. Always consult a doctor before combining with other medications.

With its affordable pricing (৳384.00 for 48 tablets) and proven efficacy, NapaDol Tablet is a trusted choice for pain relief in Bangladesh. Explore more about Paracetamol + Tramadol Hydrochloride generics and other tablet formulations for informed decisions.

Adults: 1-2 tablets every 4-6 hours (max 8 tablets/day). Renal impairment: 2 tablets every 12 hrs if CrCl <30 mL/min. Take with/without food. Limit use to ≤5 days.

The following adverse reactions may happen to this therapy: asthenia, fatigue, hot flushes, dizziness, headache, tremor, abdominal pain, constipation, diarrhea, dyspepsia, dry mouth, nausea, vomiting, anorexia, anxiety, confusion, euphoria, insomnia, nervousness, somnolence pruritus, rash, increased sweating etc.

Pregnancy Category C: Use only if benefit outweighs risk. Tramadol excreted in breast milk – may cause infant drowsiness/respiratory depression.

Avoid driving/operating machinery. Monitor LFT/RFT regularly. Don’t combine with other analgesic tablets containing same actives.

Pediatric: Not approved <18 years. Geriatric: Reduce dose by 50% in ≥65 yrs. Renal: Double dosing interval if CrCl <30. Hepatic: Contraindicated in Child-Pugh C.