Napasin Tablet 250 mg

Napasin Tablet is a prominent NSAID medication containing Naproxen Sodium (250 mg) manufactured by Skylab Pharmaceuticals Ltd. Priced at ৳4.20 per tablet, this enteric-coated tablet effectively manages inflammatory conditions like rheumatoid arthritis, osteoarthritis, and acute gout while minimizing gastric irritation.

As a non-steroidal anti-inflammatory drug (NSAID), Napasin Tablet inhibits prostaglandin synthesis, offering analgesic, antipyretic, and anti-inflammatory effects. Its 95% bioavailability ensures rapid action, making it suitable for chronic conditions requiring sustained management. The 50’s pack (৳210) provides cost-effective long-term treatment for arthritis patients.

Dosage guidelines vary by condition: adults take 500-1000 mg daily for arthritis, while acute gout requires an initial 750 mg dose. For dysmenorrhea, 500 mg followed by 250 mg every 6-8 hours proves effective. Children under 16 should avoid tablets but may use suspension formulations under medical supervision.

• Key indications: Rheumatoid arthritis, osteoarthritis, ankylosing spondylitis
• Special features: Enteric coating reduces stomach irritation
• Safety note: Contraindicated in 3rd trimester pregnancy

Drug interactions require caution with ACE inhibitors, diuretics, and blood thinners. Common side effects include heartburn (7-10% users), dizziness, and skin rashes. Store below 30°C in original packaging to maintain stability.

Skylab Pharmaceuticals ensures quality compliance in this WHO-GMP certified formulation. Patients should always consult physicians before combining with other NSAIDs or corticosteroids to avoid renal complications.

Adults: 500-1000 mg/day in divided doses for arthritis. Acute gout: 750 mg initial dose followed by 250 mg every 8 hours. Dysmenorrhea: 500 mg initial then 250 mg every 6-8 hours. Children (>2 years): 10 mg/kg/day divided twice daily. Always take with water after meals. Renal/hepatic impairment requires dose adjustment.

Most frequently reported side effects include following:

• Gastrointestinal: Heartburn, abdominal pain, nausea, diarrhea, dyspepsia.
• Central Nervous System: Headache, vertigo, drowsiness.
• Dermatological: Pruritus (itching), purpura.
• Cardiovascular: Edema, palpitation.
• Others: Visual disturbances, hearing disturbances.

Pregnancy Category C: Risk of ductus arteriosus closure in third trimester. Contraindicated during late pregnancy. Excreted minimally in breast milk – use caution during lactation.

Monitor renal/hepatic functions in prolonged use. Caution in hypertension, diabetes, elderly, alcohol users. May impair alertness – avoid driving. Cardiovascular risks require regular BP checks.

Pediatric: Suspension only for juvenile arthritis (≥2 years). Geriatric: Use lower doses. Renal impairment: Avoid if CrCl <20 mL/min. Hepatic impairment: Dose adjustment necessary.